Abstract Background mRNA expression data from next generation sequencing platforms is obtained in the form of counts per gene or exon. Counts have classically been assumed to follow a Poisson distribution in which the variance is equal to the mean. The Negative Binomial distribution which allows for over-dispersion. i. https://www.markbroyard.com/top-super-pet-naturals-busy-butter-calming-peanut-butter-for-cheap-limited-save/